CSTF1

CSTF1
Identifiers
Aliases	CSTF1, CstF-50, CstFp50, cleavage stimulation factor subunit 1
External IDs	MGI: 1914587 HomoloGene: 1012 GeneCards: CSTF1
Gene ontology Molecular function • protein binding • RNA binding Cellular component • nucleus • nucleoplasm Biological process • mRNA splicing, via spliceosome • termination of RNA polymerase II transcription • mRNA processing • mRNA 3'-end processing Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1477	67337
Ensembl	ENSG00000101138	ENSMUSG00000027498
UniProt	Q05048	Q99LC2
RefSeq (mRNA)	NM_001033521 NM_001033522 NM_001324	NM_024199
RefSeq (protein)	NP_001028693 NP_001028694 NP_001315	NP_077161
Location (UCSC)	Chr 20: 56.39 – 56.41 Mb	Chr 2: 172.37 – 172.38 Mb
PubMed search

1477

67337

ENSG00000101138

ENSMUSG00000027498

Q05048

Q99LC2

NM_001033521
NM_001033522
NM_001324

NM_024199

NP_001028693
NP_001028694
NP_001315

NP_077161

Cleavage stimulation factor 50 kDa subunit is a protein that in humans is encoded by the CSTF1 gene.

This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

CSTF1 has been shown to interact with BARD1.

...
Wikipedia