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CD120

tumor necrosis factor receptor superfamily, member 1A
Identifiers
Symbol TNFRSF1A
Alt. symbols CD120a, TNFR1
Entrez 7132
HUGO 11916
OMIM 191190
RefSeq NM_001065
UniProt P19438
Other data
Locus Chr. 12 p13.2
tumor necrosis factor receptor superfamily, member 1B
Identifiers
Symbol TNFRSF1B
Alt. symbols CD120a, TNFR2
Entrez 7133
HUGO 11917
OMIM 191191
RefSeq NM_001066
UniProt P20333
Other data
Locus Chr. 1 p36.22

CD120 (Cluster of Differentiation 120) can refer to two members of the tumor necrosis factor receptor superfamily: tumor necrosis factor receptor 1 (TNFR1) and tumor necrosis factor receptor 2 (TNFR2).

There are two variants of the receptor, each encoded by a separate gene:

TNFR1 is the receptor type responsible for mediation of TNF-alpha induced sickness behavior, and is involved in neurotoxic processes. Elevated levels of TNFR1 has been found in severe mental disorders.


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