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CCNE2

cyclin E2
Identifiers
Symbol CCNE2
Entrez 9134
HUGO 1590
OMIM 603775
RefSeq NM_057749
UniProt O96020
Other data
Locus Chr. 8 q22.1

Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27(Kip1) and p21(Cip1). It plays a role in the G1/S portion of the cell cycle and also has putative interactions with proteins CDKN1A, CDKN1B, and CDK3. Aberrant expression can lead to cancer.


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