Big Piney Creek is a river located in Ozark National Forest in the state of Arkansas. It is a tributary of the Arkansas River and therefore part of the Mississippi River watershed. Managed by the United States Forest Service, it flows for 70.8 miles (113.9 km) through Pope, Johnson and Newton counties. The headwaters of the creek are in a rugged, remote area, while the mouth of the creek empties into Lake Dardanelle on the Arkansas River.
The creek is known among kayakers and canoers for its moderately challenging Class II to Class III rapids. Although much of the land adjacent to the creek is privately owned, the Forest Service operates two campgrounds, Haw Creek Falls and Long Pool, for visitors.