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Betadine

Povidone-iodine
ExAntiseptic.jpg
Povidone-iodine applied to an abrasion using a cotton swab.
Clinical data
Trade names Wokadine, Pyodine, Betadine, others
AHFS/Drugs.com International Drug Names
Routes of
administration
Topical
ATC code
Legal status
Legal status
Identifiers
Synonyms polyvidone iodine, iodopovidone
CAS Number
PubChem CID
ChemSpider
  • none
UNII
ChEMBL
ECHA InfoCard 100.110.412
Chemical and physical data
Formula (C6H9NO)n·xI
Molar mass variable
 NYesY (what is this?)  

Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery. It may be used both to disinfect the skin of the patient and the hands of the healthcare providers. It may also be used for minor wounds. It may be applied to the skin as a liquid or a powder.

Side effects include skin irritation. If used on large wounds kidney problems, high blood sodium, and metabolic acidosis may occur. It is not recommended in people who are less than 32 weeks pregnant or taking lithium. Frequent use is not recommended in people with thyroid problems. Povidone-iodine is a chemical complex of povidone and the element iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range of microorganisms.

Povidone-iodine came into commercial use in 1955. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Providone-iodine is available as a over the counter. The wholesale cost in the developing world is about 3.30 to 11.40 USD per liter of 10% solution. This amount in the United Kingdom cost the NHS about 10.86 pounds. It is sold under a number of brand names including Betadine.


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