Avram Hershko | |
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Born | Herskó Ferenc 31 December 1937 Karcag, Hungary |
Nationality | Israel |
Fields | Chemistry |
Known for | ubiquitin-mediated protein degradation |
Notable awards | Nobel Prize in Chemistry (2004) |
Spouse | Judith Leibowitz (m. 1963) |
Children | 3 |
Avram Hershko (Hebrew: אברהם הרשקו; born 31 December 1937) is a Hungarian-born Israeli biochemist and Nobel laureate in Chemistry.
Hershko was born Herskó Ferenc in Karcag, Hungary, the son of Shoshana Margit and Moshe Hershko, both teachers. Hershko emigrated to Israel in 1950. He received his M.D. in 1965 and his Ph.D in 1969 from the Hebrew University-Hadassah Medical School, Jerusalem, Israel. He is currently a Distinguished Professor at the Rappaport Faculty of Medicine at the Technion in Haifa.
Along with Aaron Ciechanover and Irwin Rose, he was awarded the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation. The ubiquitin-proteasome pathway has a critical role in maintaining the homeostasis of cells and is believed to be involved in the development and progression of diseases such as cancer, muscular and neurological diseases, and immune and inflammatory responses.
His contributions to science directly helped cure one of his long-time friends of cancer.
Professor Hershko serves on the Scientific Advisory Board of Oramed Pharmaceuticals.