Manifold vacuum, or engine vacuum in an internal combustion engine is the difference in air pressure between the engine's intake manifold and Earth's atmosphere.
Manifold vacuum is an effect of a piston's movement on the induction stroke and the choked flow through a throttle in the intake manifold of an engine. It is a measure of the amount of restriction of airflow through the engine, and hence of the unused power capacity in the engine. In some engines, the manifold vacuum is also used as an auxiliary power source to drive engine accessories and for the crankcase ventilation system.
Manifold vacuum should not be confused with venturi vacuum, which is an effect exploited in carburetors to establish a pressure difference roughly proportional to mass airflow and to maintain a somewhat constant air/fuel ratio. It is also used in light airplanes to provide airflow for pneumatic gyroscopic instruments.
The rate of airflow through an internal combustion engine is an important factor determining the amount of power the engine generates. Most gasoline engines are controlled by limiting that flow with a throttle that restricts intake airflow, while a diesel engine is controlled by the amount of fuel supplied to the cylinder, and so has no "throttle" as such. Manifold vacuum is present in all naturally aspirated engines that use throttles (including carbureted and fuel injected gasoline engines using the Otto cycle or the two-stroke cycle; diesel engines do not have throttle plates).