Dopamine receptor antagonist Dopaminergic blockers |
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Drug class | |
Skeletal structor formula of Haloperidol, a typical antipsychotic
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Class identifiers | |
Use | Schizophrenia, bipolar disorder, nausea and vomiting, etc. |
ATC code | N05A |
Biological target | Dopamine receptors |
External links | |
MeSH | D012559 |
A dopamine antagonist (antidopaminergic) is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting.
Dopamine receptor antagonists are used for some diseases such as schizophrenia, bipolar disorder, nausea and vomiting. It can also control the symptoms of hypersexuality and increased orgasmic activity.
Antidopaminergics such as haloperidol can be an antidote for poisoning with cocaine, amphetamines and dopamine agonists such as bromocriptine and/or ropinirole.
They may include one or more of the following and last indefinitely even after cessation of the dopamine antagonist, especially after long-term or high-dosage use:
Examples of Dopamine antagonists include: