Mir Najm Zargar Gilani (Persian: میر نجم زرگر گیلانی), was an Iranian aristocrat of Gilaki origin, who was the second person to serve as the vakil (vicegerent) of the Safavid Empire.
A native of Gilan in northern Iran, Najm Zargar was originally a goldsmith in Rasht, but due to his Iranian descent was in 1507 appointed as vakil by the Safavid king Ismail I, who favored the Iranians more than the Qizilbash, who although had played a crucial role in Ismail's campaigns, possessed too much power and were no longer trust-able. However, Najm Zargar's tenure as vakil did not last long, since he later died in 1509/10, and was succeeded by Najm-e Sani.