American Airlines, Inc. (AA) is a major United States airline headquartered in Fort Worth, Texas, within the Dallas-Fort Worth metroplex. It is the world's largest airline when measured by fleet size, revenue, scheduled passengers carried, scheduled passenger-kilometers flown, and number of destinations served. American, together with its regional partners, operates an extensive international and domestic network with an average of nearly 6,700 flights per day to nearly 350 destinations in more than 50 countries.

American Airlines is a founding member of Oneworld alliance, the third largest airline alliance in the world, and coordinates fares, services, and scheduling with alliance partners British Airways, Iberia, and Finnair in the transatlantic market and with Japan Airlines in the transpacific market. Regional service is operated by independent and subsidiary carriers under the brand name American Eagle.

American operates out of ten hubs located in Dallas/Fort Worth, Charlotte, Chicago–O'Hare, Philadelphia, Miami, Phoenix–Sky Harbor, Washington–National, Los Angeles, New York–JFK, and New York–LaGuardia. American operates its primary maintenance base at Tulsa International Airport in addition to the maintenance locations located at its hubs. Dallas/Fort Worth International Airport is American Airlines’ largest passenger carrying hub, handling 51.1 million passengers annually with an average of 140,000 passengers daily. As of 2017, the company employs over 122,000 people. Through the airline's parent company, American Airlines Group, it is publicly traded under NASDAQ: AAL with a market capitalization of about $25 billion as of 2017, and included in the S&P 500 index.

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