Adrenal steroids are steroids that are derived from the adrenal glands. They include corticosteroids, which consist of glucocorticoids like cortisol and mineralocorticoids like aldosterone, adrenal androgens like dehydroepiandrosterone (DHEA) and androstenedione (A4), and neurosteroids like DHEA and DHEA sulfate (DHEA-S). Adrenal steroids are specifically produced in the zona reticularis layer of the adrenal cortex.
Adrenal steroids are distinguished from gonadal steroids, which are steroids that are derived from the gonads and include sex steroids such as progestogens like progesterone, potent androgens like testosterone, and estrogens like estradiol.