ARL2

ARL2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3DOE, 3DOF
Identifiers
Aliases	ARL2, ARFL2, ADP ribosylation factor like GTPase 2
External IDs	MGI: 1928393 HomoloGene: 1260 GeneCards: ARL2
Gene ontology Molecular function • nucleotide binding • GTP binding • GTPase inhibitor activity • protein binding • GTPase activity Cellular component • cytoplasm • centrosome • lateral plasma membrane • mitochondrial intermembrane space • intracellular • microtubule organizing center • mitochondrial matrix • mitochondrion • extracellular exosome • cytoskeleton • nucleus • nucleolus • Golgi apparatus • cytosol • focal adhesion • cilium Biological process • tubulin complex assembly • regulation of insulin secretion • small GTPase mediated signal transduction • negative regulation of GTPase activity • regulation of microtubule polymerization • bicellular tight junction assembly • positive regulation of microtubule polymerization • cell cycle • maintenance of protein location in nucleus • positive regulation of cell-substrate adhesion • centrosome cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	402	56327
Ensembl	ENSG00000213465	ENSMUSG00000024944
UniProt	P36404	Q9D0J4
RefSeq (mRNA)	NM_001667 NM_001199745	NM_019722
RefSeq (protein)	NP_001186674 NP_001658	NP_062696
Location (UCSC)	Chr 11: 65.01 – 65.02 Mb	Chr 19: 6.13 – 6.14 Mb
PubMed search

3DOE, 3DOF

402

56327

ENSG00000213465

ENSMUSG00000024944

P36404

Q9D0J4

NM_001667
NM_001199745

NM_019722

NP_001186674
NP_001658

NP_062696

ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.

The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes.

ARL2 has been shown to interact with Protein unc-119 homolog,TBCD and PDE6D.

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