A-68930

A-68930

Names
IUPAC name (1R,3S)-1-(Aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol
Identifiers
CAS Number	130465-45-1 N 130465-39-3 (HCl) Y
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL315468 N
ChemSpider	109076 Y
IUPHAR/BPS	6077
MeSH	A+68930
PubChem	122324
InChI InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 N Key: SUHGRZPINGKYNV-GJZGRUSLSA-N Y
SMILES Oc1c(O)ccc2c1C[C@H](O[C@H]2CN)c3ccccc3
Properties
Chemical formula	C16H17NO3
Molar mass	271.32 g·mol−1
log P	1.175
Acidity (pKa)	9.491
Basicity (pKb)	4.506
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

A-68930 is a synthetic compound that acts as a selective dopamine receptor D₁ partial agonist. It is orally active and has antidepressant and anorectic effects in animals, producing wakefulness and tachycardia, but without stimulant effects, instead producing sedation. The difference in effects between A-68930 and other D₁ agonists such as SKF-82958 may be due to their differing effects on the related D₅ receptor.