2016 Mutua Madrid Open – Men's Singles
| Men's Singles | |
|---|---|
| 2016 Mutua Madrid Open | |
| Champion |
 Novak Djokovic
|
| Runner-up |
 Andy Murray
|
| Final score | 6–2, 3–6, 6–3 |
Andy Murray was the defending champion, but lost in the final to Novak Djokovic, 2–6, 6–3, 3–6.
The top eight seeds receive a bye into the second round.
Click on the seed number of a player to go to their draw section.
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