The 2012 American League Championship Series was a best-of-seven playoff pitting the New York Yankees against the Detroit Tigers for the American League pennant and the right to play in the 2012 World Series. The series, the 43rd in league history, began on Saturday, October 13 in New York and ended on Thursday, October 18 in Detroit. The Tigers won the series 4–0.TBS televised all games in the United States. In global markets, MLB International broadcast the ALCS in its entirety, with long-time Baltimore Orioles announcer Gary Thorne and ESPN's Rick Sutcliffe calling the games.

This was the third postseason meeting between the Yankees and the Tigers, but the first in the ALCS. The Tigers previously beat the Yankees in the 2006 ALDS (3–1) and the 2011 ALDS (3–2). The last appearance for each team in the ALCS resulted in a loss to the Texas Rangers; the Yankees in the 2010 ALCS and the Tigers in the 2011 ALCS.

Detroit won the series, 4–0.

†: postponed from October 17 due to rain

Saturday, October 13, 2012 – 8:07 p.m. (EDT) at Yankee Stadium in Bronx, New York

The Yankees threatened in the first inning when they loaded the bases, but Jhonny Peralta robbed Alex Rodriguez of an RBI single with a diving stop to end the inning. Peralta also took away a run in the second when, with the bases loaded and two outs once again, Robinson Canó hit a ball that glanced off the wrist of Tiger starter Doug Fister and caromed to shortstop. Peralta fielded it and just nipped Canó at first, which was revealed to be the wrong call. The Yankees would leave the bases loaded for the third time in the game in the sixth inning, and were 1-for-10 with runners in scoring position, with the only hit being an infield single that did not score a run.

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