The 2008 NCAA Division I Men's Basketball Championship Game was the finals of the 2008 NCAA Division I Men's Basketball Tournament and it determined the national champion for the 2007-08 NCAA Division I men's basketball season. The 2008 national title game was played on April 7, 2008 at the Alamodome in San Antonio, Texas. The 2008 national title game was played between the 2008 South Regional Champions, #1-seeded Memphis the 2008 Midwest Regional Champions, #1-seeded Kansas.

For the second consecutive year, the national title game was played between two #1 seeds, due to the fact that all four #1 seeds were in the Final Four for the first time in NCAA Tournament history.

Kansas entered the 2008 NCAA Tournament as the #1 seed in the Midwest Regional. In the 1st round of the 2008 NCAA Tournament, Kansas dominated Portland State with a 85-61 victory. In the 2nd round of the 2008 NCAA Tournament, Kansas beat UNLV 75-56 to advance to the Sweet 16. In the Sweet 16 of the 2008 NCAA Tournament, Kansas beat Villanova 72-57 to advance to the Elite Eight. In the Elite Eight of the 2008 NCAA Tournament, Kansas was able to overcome Stephen Curry's 25 points to beat Davidson 59-57 and advance to the 2008 Final Four. In the 2008 Final Four, Brandon Rush scored 25 points to beat North Carolina 84-66 to advance to the 2008 national title game.

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