The 2007–08 NCAA Division I men's basketball season began on November 5, 2007 ended with the 2008 NCAA Men's Division I Basketball Tournament's championship game on April 7, 2008, in the Alamodome in San Antonio, Texas.

Beginning in 2007-08, the following rules changes were implemented:

The top 25 from the AP and ESPN/USA Today Coaches Polls November 5, 2007.

Thirty athletic conferences each end their regular seasons with a single-elimination tournament. The teams in each conference that win their regular season title are given the number one seed in each tournament. The winners of these tournaments receive automatic invitations to the 2008 NCAA Men's Division I Basketball Tournament. The Ivy League doesn't have a conference tournament, and Cornell, who won the regular season title, received their automatic invitation.

The NCAA Tournament tipped off on March 18, 2008 with the opening round game in Dayton, Ohio, and concluded on April 7 at the Alamodome in San Antonio, Texas. Of the 65 teams that were invited to participate, 31 were automatic bids while 34 were at-large bids. The 34 at-large teams came from 10 conferences, with the Big East tying its own 2006 record with eight bids. Three other conferences, the Big 12, Pac-10, and SEC, had six teams invited to the tournament. Notably absent from the field were Florida and Ohio State, the champions and runners-up of the 2007 Tournament, the first time that both teams from a previous year's finals failed to make the tournament since 1980.Kansas defeated Memphis, 75–68 in overtime to win their third NCAA Tournament championship, and Jayhawks guard Mario Chalmers was named the tournament's Most Outstanding Player.

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