2006 Pilot Pen Tennis – Men's Singles
| Men's Singles | |
|---|---|
| 2006 Pilot Pen Tennis | |
| Champion |
 Nikolay Davydenko
|
| Runner-up |
 Agustín Calleri
|
| Final score | 6–4, 6–3 |
James Blake was the defending champion, but lost to Rubén Ramírez Hidalgo in the second round.
Nikolay Davydenko won the title, defeating Agustín Calleri 6–4, 6–3 in the final.
All seeds receive a bye into the second round.
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