2005 Mutua Madrileña Masters Madrid – Singles
| Singles | |
|---|---|
| 2005 Mutua Madrileña Masters Madrid | |
| Champion |
 Rafael Nadal
|
| Runner-up |
 Ivan Ljubičić
|
| Final score | 3–6, 2–6, 6–3, 6–4, 7–6 (7–3) |
Marat Safin was the defending champion, but chose not to compete this year. Rafael Nadal won the title, defeating Ivan Ljubičić in the final in 5 sets.
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated. All sixteen seeds received a bye into the second round.
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