The 2000–01 Los Angeles Lakers season was the 53rd season of the franchise, 53rd in the National Basketball Association (NBA) and 41st in Los Angeles. During the offseason, the Lakers acquired Horace Grant from the Seattle SuperSonics. Grant won three championships with the Chicago Bulls in the early 1990s. They also signed free agent Isaiah Rider, who previously played for the Atlanta Hawks. The Lakers finished the regular season with a 56–26 record, and won the Pacific Division over the rival Sacramento Kings by one game. Kobe Bryant and Shaquille O'Neal were both selected for the 2001 NBA All-Star Game, but O'Neal did not play due to an injury. The Lakers clinched the second seed in the playoffs.

In the playoffs, the Lakers swept the Portland Trail Blazers in the first round, swept the Kings in the semifinals, then swept the top–seeded San Antonio Spurs the Western Conference Finals. They went on to win the NBA Finals 4–1 against the Philadelphia 76ers, earning the franchise its 13th NBA championship. It was the second of the Lakers' three-peat championships to begin the millennium.

Following the season, Grant re-signed as a free agent with the Orlando Magic, Rider signed with the Denver Nuggets, Tyronn Lue signed with the Washington Wizards and Ron Harper retired.

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