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2-Aminopyridine

2-Aminopyridine
2-aminopyridine.svg
Names
IUPAC name
Pyridin-2-amine
Other names
2-Pyridinamine; 2-Pyridylamine; α-Aminopyridine; α-Pyridylamine
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.007.263
PubChem CID
Properties
C5H6N2
Molar mass 94.12 g·mol−1
Appearance colourless solid
Melting point 59 to 60 °C (138 to 140 °F; 332 to 333 K)
Boiling point 210 °C (410 °F; 483 K)
>100%
Hazards
Flash point 68 °C; 154 °F; 341 K
Lethal dose or concentration (LD, LC):
LD50 (median dose)
200 mg/kg (rat, oral)
50 mg/kg (mouse, oral)
US health exposure limits (NIOSH):
PEL (Permissible)
TWA 0.5 ppm (2 mg/m3)
REL (Recommended)
TWA 0.5 ppm (2 mg/m3)
IDLH (Immediate danger)
5 ppm
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY  (what is YesYN ?)
Infobox references

2-Aminopyridine is an organic compound with the formula H2NC5H4N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.

Although 2-hydroxypyridine exists in significant amounts as the pyridone tautomer, the related imine tautomer (HNC5H4NH) is less important for 2-aminopyridine.


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