Names | |
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IUPAC name
Pyridin-2-amine
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Other names
2-Pyridinamine; 2-Pyridylamine; α-Aminopyridine; α-Pyridylamine
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Identifiers | |
3D model (Jmol)
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ChemSpider | |
ECHA InfoCard | 100.007.263 |
PubChem CID
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Properties | |
C5H6N2 | |
Molar mass | 94.12 g·mol−1 |
Appearance | colourless solid |
Melting point | 59 to 60 °C (138 to 140 °F; 332 to 333 K) |
Boiling point | 210 °C (410 °F; 483 K) |
>100% | |
Hazards | |
Flash point | 68 °C; 154 °F; 341 K |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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200 mg/kg (rat, oral) 50 mg/kg (mouse, oral) |
US health exposure limits (NIOSH): | |
PEL (Permissible)
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TWA 0.5 ppm (2 mg/m3) |
REL (Recommended)
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TWA 0.5 ppm (2 mg/m3) |
IDLH (Immediate danger)
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5 ppm |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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what is ?) | (|
Infobox references | |
2-Aminopyridine is an organic compound with the formula H2NC5H4N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.
Although 2-hydroxypyridine exists in significant amounts as the pyridone tautomer, the related imine tautomer (HNC5H4NH) is less important for 2-aminopyridine.