The 1963 Major League Baseball All-Star Game was the 34th playing of the midsummer classic between the all-stars of the American League (AL) and National League (NL), the two leagues comprising Major League Baseball. The game was held on July 9, 1963 in Cleveland, Ohio, at Cleveland Municipal Stadium, home of the American League's Cleveland Indians. The game was won by the National League 5–3.

From 1959 to 1962, baseball experimented with a pair of All-Star Games per year. That ended with this 1963 game, which also marked the 30th anniversary of the inaugural All-Star Game played in Chicago in 1933.

The teams traded runs in the second inning. Willie Mays drew a walk off Ken McBride, stole second and scored on a Dick Groat single. The AL tied the score when Jim O'Toole gave up a Leon Wagner single, hit Zoilo Versalles with a pitch and surrendered an RBI hit to his pitching counterpart, McBride.

In the third, both sides scored twice. Behind 3-1, the AL struck back on a double by Albie Pearson and singles by Frank Malzone and Earl Battey to tie it at 3-all.

The NL scratched out a run off Jim Bunning in the fifth to regain the lead, then made it 5-3 in the eighth when Bill White singled off Dick Radatz, stole second and scored on a Ron Santo single. Don Drysdale closed it out in the eighth and ninth, retiring Bobby Richardson on a game-ending double play.

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