1959 U.S. National Championships – Men's Singles
| Men's Singles | |
|---|---|
| 1959 U.S. National Championships | |
| Champion |
 Neale Fraser
|
| Runner-up |
 Alex Olmedo
|
| Final score | 6–3, 5–7, 6–2, 6–4 |
Neale Fraser defeated Alex Olmedo 6–3, 5–7, 6–2, 6–4 in the final to win the Men's Singles tennis title at the 1959 U.S. National Championships.
The seeded players are listed below. Neale Fraser is the champion; others show the round in which they were eliminated.
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