GLUT1

SLC2A1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4PYP, 5EQH, 5EQI, 5EQG
Identifiers
Aliases	SLC2A1, CSE, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1, GLUT1DS, HTLVR, PED, SDCHCN, solute carrier family 2 member 1
External IDs	OMIM: 138140 MGI: 95755 HomoloGene: 68520 GeneCards: SLC2A1
Gene ontology Molecular function • substrate-specific transmembrane transporter activity • xenobiotic transporter activity • transmembrane transporter activity • transporter activity • protein self-association • kinase binding • protein binding • identical protein binding • dehydroascorbic acid transporter activity • glucose transmembrane transporter activity • D-glucose transmembrane transporter activity Cellular component • cytoplasm • integral component of membrane • vesicle • cytosol • blood microparticle • membrane • cell-cell junction • melanosome • Golgi membrane • plasma membrane • integral component of plasma membrane • intracellular • female pronucleus • basolateral plasma membrane • midbody • apical plasma membrane • cortical actin cytoskeleton • caveola • membrane raft • extracellular exosome Biological process • L-ascorbic acid metabolic process • cellular response to glucose starvation • protein complex assembly • regulation of insulin secretion • xenobiotic transport • response to osmotic stress • lactose biosynthetic process • transport • glucose transport • dehydroascorbic acid transport • carbohydrate transport • transmembrane transport • glucose transmembrane transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6513	20525
Ensembl	ENSG00000117394	ENSMUSG00000028645
UniProt	P11166	P17809
RefSeq (mRNA)	NM_006516	NM_011400
RefSeq (protein)	NP_006507	NP_035530.2 NP_035530
Location (UCSC)	Chr 1: 42.93 – 42.96 Mb	Chr 4: 119.11 – 119.14 Mb
PubMed search

4PYP, 5EQH, 5EQI, 5EQG

6513

20525

ENSG00000117394

ENSMUSG00000028645

P11166

P17809

NM_006516

NM_011400

NP_006507

NP_035530.2
NP_035530

Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells.

GLUT1 was the first glucose transporter to be characterized. GLUT 1 is highly conserved. GLUT 1 of humans and mice have 98% identity at the amino acid level. GLUT 1 is encoded by the SLC2 gene and is one of a family of 14 genes encoding GLUT proteins.

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Wikipedia