Zinc acetate

Zinc acetate

Names
IUPAC name Zinc acetate
Other names Acetic acid, Zinc salt Acetic acid, Zinc(II) salt Dicarbomethoxyzinc Zinc diacetate
Identifiers
CAS Number	557-34-6 Y 5970-45-6 N
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL1200928 N
ChemSpider	10719 Y
ECHA InfoCard	100.008.338
E number	E650 (flavour enhancer)
PubChem	11192
RTECS number	ZG8750000
UNII	H2ZEY72PME Y
InChI InChI=1S/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2 Y Key: DJWUNCQRNNEAKC-UHFFFAOYSA-L Y InChI=1/2C2H4O2.Zn/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2 Key: DJWUNCQRNNEAKC-NUQVWONBAP
SMILES [Zn+2].[O-]C(=O)C.[O-]C(=O)C
Properties
Chemical formula	ZnC4H6O4 (dihydrate)
Molar mass	219.50 g/mol (dihydrate) 183.48 g/mol (anhydrous)
Appearance	White solid (all forms)
Density	1.735 g/cm3 (dihydrate)
Melting point	Decomposes at 237 °C (459 °F; 510 K) (dihydrate loses water at 100 °C)
Boiling point	decomposes
Solubility in water	43 g/100 mL (20 °C, dihydrate)
Solubility	soluble in alcohol
Magnetic susceptibility (χ)	−101.0·10−6 cm3/mol (+2 H2O)
Structure
Coordination geometry	octahedral (dihydrate)
Molecular shape	tetrahedral
Pharmacology
ATC code	A16AX05 (WHO)
Hazards
Main hazards	mildly toxic
R-phrases	R22 R36 R50/53
S-phrases	S26 S60 S61
Related compounds
Other anions	Zinc chloride
Other cations	Copper(II) acetate
Related compounds	Basic beryllium acetate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Zinc acetate is a salt with the formula Zn(O₂CCH₃)₂, which commonly occurs as the dihydrate Zn(O₂CCH₃)₂(H₂O)₂. Both the hydrate and the anhydrous forms are colorless solids that are commonly used in chemical synthesis and as dietary supplements. Zinc acetates are prepared by the action of acetic acid on zinc carbonate or zinc metal. When used as a food additive, it has the E number E650.

In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures. In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups.

In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.

Heating Zn(CH₃CO₂)₂ in a vacuum results in a loss of acetic anhydride, leaving a residue of basic zinc acetate, with the formula Zn₄O(CH₃CO₂)₆. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be₄O(OAc)₆.

Zinc acetate has been used in lozenges for treating the common cold. Pooling the results of three high dose zinc acetate trials indicates an average 42% reduction in the duration of colds (see figure).