ZIP9

SLC39A9
Identifiers
Aliases	SLC39A9, ZIP-9, ZIP9, solute carrier family 39 member 9
External IDs	MGI: 1914820 HomoloGene: 6935 GeneCards: SLC39A9
Gene ontology Molecular function • metal ion transmembrane transporter activity Cellular component • integral component of membrane • membrane Biological process • metal ion transport • zinc II ion transport • ion transport • transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55334	328133
Ensembl	ENSG00000029364	ENSMUSG00000048833
UniProt	Q9NUM3	Q8BFU1
RefSeq (mRNA)	NM_001252148 NM_001252150 NM_001252151 NM_001252152 NM_018375 NM_001330185	NM_026244
RefSeq (protein)	NP_001239077 NP_001239079 NP_001239080 NP_001239081 NP_001317114 NP_060845	NP_080520
Location (UCSC)	Chr 14: 69.4 – 69.46 Mb	Chr 12: 80.64 – 80.68 Mb
PubMed search

55334

328133

ENSG00000029364

ENSMUSG00000048833

Q9NUM3

Q8BFU1

NM_001330185

NM_026244

NP_060845

NP_080520

Zrt- and Irt-like protein 9 (ZIP9), also known as solute carrier family 39 member 9 (SLC39A9), is a protein which is encoded by the SLC39A9 gene. It is a membrane androgen receptor (mAR) coupled to G proteins and a zinc transporter protein. Through activation of ZIP9, testosterone has been found to increase intracellular zinc levels in breast cancer, prostate cancer, and ovarian follicle cells and to induce apoptosis in these cells, an action which may be mediated partially or fully by increased zinc concentrations.

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Wikipedia