YqeY
| YqeY | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of cytosolic protein of unknown function YqeY from Bacillus subtilis
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| Identifiers | |||||||||
| Symbol | YqeY | ||||||||
| Pfam | PF09424 | ||||||||
| Pfam clan | CL0279 | ||||||||
| InterPro | IPR019004 | ||||||||
| SCOP | 1ng5 | ||||||||
| SUPERFAMILY | 1ng5 | ||||||||
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| Available protein structures: | |
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| Pfam | structures |
| PDB | RCSB PDB; PDBe; PDBj |
| PDBsum | structure summary |
In molecular biology, YqeY is a type of protein domain of unknown function. It is thought to have a role in protein synthesis, facilitating the production of charged transfer RNA used in the process of translating mRNA into protein. It is present as a domain of glutaminyl-tRNA synthetase (GlnRS) in almost all eukaryotes.
The YqeY domain has been found to be involved in the recognition of tRNA charged with the amino acid glutamine (tRNA-Gln). In some cases YqeY also increases the affinity of GlnRS for tRNA-Gln, but only when present in cis (that is, as part of the GlnRS polypeptide chain). However, the presence of YqeY as a standalone domain in organisms without GlnRS suggests that YqeY domains may have additional cellular functions.
This protein domain shares sequence homology with the C-terminal domain of GatB and GatE, the tRNA-binding subunits of bacterial and archaeal glutamine amidotransferases.
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