"Yo (Excuse Me Miss)" is the second single from Chris Brown's debut album Chris Brown, released in November 2005 in the U.S. and February 2006 worldwide. "Yo (Excuse Me Miss)", produced by Dre & Vidal, became Brown's second top ten single in the U.S., peaking at No. 7 on February 18, 2006. It has been certified platinum by the RIAA. In other countries, the song reached number thirteen in the United Kingdom and number ten in Australia.

It features Dre (André Merit) who sings the chorus' background vocals.

This song has appeared on the videogame Dance Dance Revolution Hottest Party.

Andy Kellman of AllMusic highlighted this song

In the music video, directed by Erik White, it features model and former Love and Hiphop star Erica Mena as a girl Brown sees that catches his attention. He then follows the girls while dancing. After arriving at a basketball court, he begins to dance with two other guys. Brown then gets inside a car with the girl and sings to her. They get close, then she gives him her phone to put his number in. He soon dances on a car and at the end of the video he begins to dance with a crowd of people. The video features the first verse of "Gimme That" at the end. Lil' JJ, Trey Songz, and DeRay Davis make cameo appearances in the video. The video made a reference to Michael Jackson's 1987 hit single "The Way You Make Me Feel".

On April 1, 2006, Chris Brown performed "Yo (Excuse Me Miss)" at the 2006 Kids' Choice Awards as part of a musical duel with rapper Bow Wow inspired by the 1986 Run-D.M.C. music video "Walk This Way".

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