Yellapragada Subbarow
| Yellapragada Subbarow | |
|---|---|
 |
|
| Native name | యల్లాప్రగడ సుబ్బారావు |
| Born |
12 January 1895 Bhimavaram, Madras Presidency, British India (now in Andhra Pradesh, India) |
| Died | 8 August 1948 (aged 53) New York City, United States |
| Nationality | Indian |
| Fields | Biochemistry |
| Institutions | Lederle Laboratories, a division of American Cyanamid (Acquired by Wyeth in 1994, now Pfizer) |
| Alma mater |
Harvard Medical School Madras Medical College |
| Known for | Discovering the role of phosphocreatine and adenosine triphosphate in muscular activity; synthesis of folic acid; synthesis of methotrexate; discovery of diethylcarbamazine |
| Influenced |
Benjamin Minge Duggar George H. Hitchings |
Yellapragada Subbarow (12 January 1895 – 8 August 1948) was an Indian biochemist who discovered the function of adenosine triphosphate as an energy source in the cell, and developed methotrexate for the treatment of cancer. Most of his career was spent in the United States. Despite his isolation of ATP, Subbarow was denied tenure at Harvard though he would lead some of America's most important medical research during World War II. He is also credited with the first synthesis of the chemical compounds folic acid and methotrexate. Subbarow died in the United States.
Subbarow's colleague, George Hitchings said, "Some of the nucleotides isolated by Subbarow had to be rediscovered years later by other workers because Fiske, apparently out of jealousy, did not let Subbarow's contributions see the light of the day." A fungus genus hes been named Subbaromyces in his honor. Writing in the April 1950 issue of Argosy, Doron K. Antrim observed, "You've probably never heard of Dr. Yellapragada Subbarow. Yet because he lived you may be alive and are well today. Because he lived you may live longer."
He was born in Bhimavaram, Madras Presidency, now in West Godavari District, Andhra Pradesh in India. He passed through a traumatic period in his schooling at Rajahmundry (due to the premature death of close relatives by disease) and eventually matriculated in his third attempt from the Hindu High School, Madras. He passed the Intermediate Examination from the Presidency College and entered the Madras Medical College where his education was supported by friends and Kasturi Suryanarayana Murthy, whose daughter he later married.
...
Wikipedia