Names | |
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IUPAC name
4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]pyran-2-one
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Identifiers | |
500-62-9 | |
3D model (Jmol) | Interactive image |
ChEMBL | ChEMBL1098658 |
ChemSpider | 4444896 |
ECHA InfoCard | 100.211.821 |
PubChem | 5281575 |
UNII | R970U49V3C |
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Properties | |
C15H14O4 | |
Molar mass | 258.27 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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what is ?) | (|
Infobox references | |
Yangonin is one of the six major kavalactones found in the kava plant. It has been shown to possess binding affinity for the cannabinoid receptor CB1 (Ki = 0.72 μM), where it behaves as an agonist.
Yangonin displays marked in vitro toxicity on human with approximately 40% reduction in viability based on an ethidium bromide assay. The predominant mode of cell death turned out to be apoptosis rather than necrosis. No significant changes were observed in glutathione levels.