YAP1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1JMQ, 1K5R, 1K9Q, 1K9R, 2LAW, 2LAX, 2LAY, 2LTV, 2LTW, 3KYS, 3MHR, 4RE1, 4REX

Identifiers

Aliases

YAP1, COB1, YAP, YAP2, YAP65, YKI, Yes associated protein 1, Yap

External IDs

MGI: 103262 HomoloGene: 4452 GeneCards: YAP1

Genetically Related Diseases

polycystic ovary syndrome

Gene ontology
Molecular function	• transcription corepressor activity • transcription coactivator activity • chromatin binding • transcription factor activity, RNA polymerase II transcription factor binding • protein C-terminus binding • protein binding • transcription regulatory region DNA binding • proline-rich region binding • RNA polymerase II core promoter sequence-specific DNA binding
Cellular component	• cytoplasm • cytosol • membrane • transcription factor complex • nucleoplasm • nucleus
Biological process	• cellular response to retinoic acid • regulation of metanephric nephron tubule epithelial cell differentiation • regulation of transcription, DNA-templated • somatic stem cell population maintenance • lateral mesoderm development • bud elongation involved in lung branching • positive regulation of canonical Wnt signaling pathway • regulation of canonical Wnt signaling pathway • negative regulation of extrinsic apoptotic signaling pathway • contact inhibition • notochord development • positive regulation of organ growth • hippo signaling • transcription, DNA-templated • keratinocyte differentiation • negative regulation of stem cell differentiation • cellular response to DNA damage stimulus • vasculogenesis • regulation of cell proliferation • embryonic heart tube morphogenesis • cellular response to gamma radiation • cell morphogenesis • positive regulation of cell proliferation • lung epithelial cell differentiation • regulation of keratinocyte proliferation • transcription initiation from RNA polymerase II promoter • cell proliferation • positive regulation of stem cell population maintenance • negative regulation of epithelial cell differentiation • regulation of neurogenesis • regulation of stem cell proliferation • positive regulation of transcription from RNA polymerase II promoter • paraxial mesoderm development • negative regulation of nucleic acid-templated transcription
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


10413


22601

Ensembl


ENSG00000137693


ENSMUSG00000053110

UniProt


P46937


P46938

RefSeq (mRNA)

NM_001130145 NM_001195044 NM_001195045 NM_001282097 NM_001282098
NM_001282099 NM_001282100 NM_001282101 NM_006106


NM_001171147 NM_009534

RefSeq (protein)

NP_001123617 NP_001181973 NP_001181974 NP_001269026 NP_001269027
NP_001269028 NP_001269029 NP_001269030 NP_006097


NP_001164618.1 NP_033560.1 NP_001164618 NP_033560

Location (UCSC)

Chr 11: 102.11 – 102.23 Mb

Chr 9: 7.93 – 8 Mb

PubMed search

1JMQ, 1K5R, 1K9Q, 1K9R, 2LAW, 2LAX, 2LAY, 2LTV, 2LTW, 3KYS, 3MHR, 4RE1, 4REX

NM_001282099
NM_001282100
NM_001282101
NM_006106

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