XIAP

XIAP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1F9X, 1G3F, 1G73, 1I3O, 1I4O, 1I51, 1KMC, 1NW9, 1TFQ, 1TFT, 2ECG, 2JK7, 2KNA, 2OPY, 2OPZ, 2POI, 2POP, 2QRA, 2VSL, 3CLX, 3CM2, 3CM7, 3EYL, 3G76, 3HL5, 3UW4, 3UW5, 4EC4, 4HY0, 4IC2, 4IC3, 4J3Y, 4J44, 4J45, 4J46, 4J47, 4J48, 4KJU, 4KJV, 4KMP, 4MTZ, 4OXC, 4WVS, 4WVT, 4WVU, 5C0K, 5C0L, 5C3H, 5C3K, 5C7A, 5C7B, 5C7C, 5C7D, 5C83, 5C84
Identifiers
Aliases	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3, X-linked inhibitor of apoptosis
External IDs	MGI: 107572 HomoloGene: 901 GeneCards: XIAP
Gene ontology Molecular function • cysteine-type endopeptidase inhibitor activity involved in apoptotic process • ubiquitin-protein transferase activity • peptidase inhibitor activity • cysteine-type endopeptidase inhibitor activity • protein binding • zinc ion binding • ubiquitin protein ligase activity • metal ion binding • identical protein binding • transferase activity Cellular component • nucleus • nucleoplasm • cytosol • cytoplasm Biological process • regulation of inflammatory response • mitotic spindle assembly • regulation of cell proliferation • regulation of innate immune response • negative regulation of peptidase activity • positive regulation of protein linear polyubiquitination • copper ion homeostasis • regulation of nucleotide-binding oligomerization domain containing signaling pathway • cellular response to DNA damage stimulus • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • inhibition of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of canonical Wnt signaling pathway • regulation of BMP signaling pathway • positive regulation of protein ubiquitination • Wnt signaling pathway • negative regulation of apoptotic process • protein ubiquitination • apoptotic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	331	11798
Ensembl	ENSG00000101966	ENSMUSG00000025860
UniProt	P98170	Q60989
RefSeq (mRNA)	NM_001167 NM_001204401	NM_001301639 NM_001301641 NM_009688
RefSeq (protein)	NP_001158 NP_001191330	NP_001288568.1 NP_001288570.1 NP_033818.2 NP_001288568 NP_001288570 NP_033818
Location (UCSC)	Chr X: 123.86 – 123.91 Mb	Chr X: 42.06 – 42.11 Mb
PubMed search

1F9X, 1G3F, 1G73, 1I3O, 1I4O, 1I51, 1KMC, 1NW9, 1TFQ, 1TFT, 2ECG, 2JK7, 2KNA, 2OPY, 2OPZ, 2POI, 2POP, 2QRA, 2VSL, 3CLX, 3CM2, 3CM7, 3EYL, 3G76, 3HL5, 3UW4, 3UW5, 4EC4, 4HY0, 4IC2, 4IC3, 4J3Y, 4J44, 4J45, 4J46, 4J47, 4J48, 4KJU, 4KJV, 4KMP, 4MTZ, 4OXC, 4WVS, 4WVT, 4WVU, 5C0K, 5C0L, 5C3H, 5C3K, 5C7A, 5C7B, 5C7C, 5C7D, 5C83, 5C84

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