Wnt2b

WNT2B

Identifiers

WNT2B, WNT13, Wnt family member 2B

External IDs

MGI: 1261834 HomoloGene: 22526 GeneCards: WNT2B

Gene ontology
Molecular function	• frizzled binding • receptor binding
Cellular component	• proteinaceous extracellular matrix • extracellular region • extracellular space • intracellular membrane-bounded organelle
Biological process	• cell fate commitment • positive regulation of branching involved in ureteric bud morphogenesis • male gonad development • chondrocyte differentiation • positive regulation of canonical Wnt signaling pathway • iris morphogenesis • cornea development in camera-type eye • cellular response to starvation • hematopoietic stem cell proliferation • lung induction • multicellular organism development • forebrain regionalization • lens development in camera-type eye • neuron differentiation • mesenchymal-epithelial cell signaling • canonical Wnt signaling pathway • Wnt signaling pathway
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


7482


22414

Ensembl


ENSG00000134245


ENSMUSG00000027840

UniProt


Q93097


O70283

RefSeq (mRNA)


NM_024494 NM_001291880 NM_004185


NM_009520

RefSeq (protein)


NP_001278809 NP_004176 NP_078613


NP_033546.2 NP_033546

Location (UCSC)

Chr 1: 112.47 – 112.53 Mb

Chr 3: 104.95 – 104.96 Mb

PubMed search

NM_024494
NM_001291880
NM_004185

NM_009520

NP_001278809
NP_004176
NP_078613

NP_033546.2
NP_033546

Protein Wnt-2b (formerly Wnt13) is a protein that in humans is encoded by the WNT2B gene.

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.

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