Wilson disease protein

ATP7B

PBB Protein ATP7B image.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2ROP, 2EW9, 2KOY, 2LQB

Identifiers

ATP7B, PWD, WC1, WD, WND, ATPase copper transporting beta

External IDs

OMIM: 606882 MGI: 103297 HomoloGene: 20063 GeneCards: ATP7B

Gene ontology
Molecular function	• nucleotide binding • metal ion binding • copper-exporting ATPase activity • cation-transporting ATPase activity • protein binding • copper ion binding • hydrolase activity • ATP binding • copper-transporting ATPase activity • copper ion transmembrane transporter activity
Cellular component	• cytoplasm • integral component of membrane • trans-Golgi network membrane • membrane • Golgi membrane • integral component of plasma membrane • trans-Golgi network • basolateral plasma membrane • mitochondrion • perinuclear region of cytoplasm • endosome • late endosome • Golgi apparatus • cytoplasmic vesicle
Biological process	• intracellular copper ion transport • copper ion transmembrane transport • metal ion transport • copper ion import • cation transport • ion transport • copper ion export • ion transmembrane transport • sequestering of calcium ion • cellular zinc ion homeostasis • cellular copper ion homeostasis • lactation • response to copper ion • copper ion transport • ATP hydrolysis coupled cation transmembrane transport • transport
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE ATP7B 204624 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


540


11979


ENSG00000123191


ENSMUSG00000006567


P35670


Q64446

RefSeq (mRNA)


NM_000053 NM_001005918 NM_001243182 NM_001330578 NM_001330579


NM_007511

RefSeq (protein)

NP_000044 NP_001005918 NP_001230111 NP_001317507 NP_001317508
NP_000044.2 NP_000044.2 NP_001005918.1 NP_001230111.1


NP_031537

Location (UCSC)

Chr 13: 51.93 – 52.01 Mb

Chr 8: 21.99 – 22.06 Mb

PubMed search

2ROP, 2EW9, 2KOY, 2LQB

ENSG00000123191

ENSMUSG00000006567

NM_000053
NM_001005918
NM_001243182
NM_001330578
NM_001330579

NP_000044.2
NP_000044.2
NP_001005918.1
NP_001230111.1

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Wikipedia

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