William Whitaker (1548–1595) was a prominent Protestant Calvinistic Anglican churchman, academic, and theologian. He was Master of St. John's College, Cambridge, and a leading divine in the university in the latter half of the sixteenth century. His uncle was Alexander Nowell, the Dean of St. Paul's Cathedral and catechist.
He was born at Holme, near Burnley, Lancashire, in 1548, being the third son of Thomas Whitaker of that place, by Elizabeth his wife, daughter of John Nowell, esq., of Read, and sister of Alexander Nowell, dean of St Paul's." After receiving the rudiments of learning at his native parish school, he was sent by his uncle, Alexander Nowell, to St Paul's School in London. (Alexander Nowell, a Marian exile, a fugitive from the "burning times" of Anglo-Italian policies, 1553–1558, was also a Protestant, Reformed and Anglican Churchman.) Whittaker thence proceeded to Cambridge, where he matriculated as a pensioner of Trinity College on 4 October 1564. He was subsequently elected a scholar on the same foundation, proceeded B.A. in March 1568, and on 6 September 1569 was elected to a minor fellowship, and on 25 March 1571 to a major fellowship, at his college. In 1571 he commenced M.A. Throughout his earlier career at the university he was assisted by his uncle, who granted him leases, "freely and without fine," towards defraying his expenses. Whitaker evinced his gratitude by dedicating to Nowell a translation of the Book of Common Prayer into Greek, and a like version of Nowell's own larger catechism from the Latin into Greek.
The marked ability with which he acquitted himself when presiding as "father of the philosophy act" at an academic commencement appears to have first brought him prominently into notice. He also became known as an indefatigable student of the scriptures, the commentators, and the schoolmen, and was very early in his career singled out by John Whitgift, at that time master of Trinity, for marks of special favour. On 3 February 1578 he was installed canon of Norwich Cathedral, and in the same year was admitted to the degree of B.D., and incorporated on 14 July at Oxford. In 1580 he was appointed by the crown to the regius professorship of divinity, to which Elizabeth shortly after added the chancellorship of St. Paul's, London, and from this time his position as the champion of the teaching of the Protestant and Reformed Church of England appears to have been definitely taken up. In 1582, on taking part in a disputation at commencement, he took for his thesis, Pontifex Romanus est ille Antichristus, quern futurum Scriptura prædixit, or, The Roman Pope is that Antichrist which the Scriptures Foretold. His lectures, as professor, afterwards published from shorthand notes taken by John Allenson, a fellow of St. John's, were mainly directed towards refuting Roman Catholic theologians, especially Robert Bellarmine and Thomas Stapleton. He also severely criticised the just-published Douay version of the New Testament, thereby becoming involved in a controversy with William Rainolds.