William Talbot, 1st Earl Talbot PC (16 May 1710 – 27 April 1782), known as the Lord Talbot from 1737 to 1761, was a British politician.
Talbot was born at Worcester, the son of Charles Talbot, later Baron Talbot. He was educated at Eton from 1725 to 1728 and matriculated at Exeter College, Oxford on 23 January 1727. He was created DCL (Doctor of Civil Law) on 12 June 1736. He was Member of Parliament for Glamorganshire from 1734 to 1737, when he succeeded his father in the barony and entered the House of Lords. He was Lord High Steward at King George III's coronation, and became a member of the Privy Council in 1761. He served from then until his death as Lord Steward of the Household. He was created Earl Talbot on 29 March 1761.
Talbot died 27 April 1782 at Lincolns Inn Fields and was buried at Sutton.
Talbot had no sons so he was created Baron Dynevor, of Dynevor in the county of Carmarthen on 17 October 1780, with a special remainder in favour of his only child, a daughter, Cecil Rice, and the heirs male of her body.