William Hull Caine (1799–1871) was the Colonial Secretary of Hong Kong from 1854 to 1859. He attained the rank of Lieutenant Colonel prior to his secretary appointment. Caine was also the acting Governor of Hong Kong between May and September 1859.
Captain Caine was born in England in 1799 and served in the British Army's 26th (Cameronian) Regiment of Foot during the Peninsular War against Napoleon in Spain. His regiment was later transferred to Hong Kong and he began his long association with the colony.
Caine was Chief Magistrate, the head of pre-Hong Kong Police Force from 1841 to 1844. The then Major Caine was appointed Colonial Secretary and Auditor General from 1846 to 1854. He was the Colonial Secretary of Hong Kong from 1854 to 1859. He was the acting Governor of Hong Kong between May and September 1859.
Caine had four sons, Charles Henry Fearon Caine, Henry Monteith Caine, George Whittingham Caine, William Hull Caine.
Caine retired and left Hong Kong in 1859 and died in 1871.
Caine Road on Mid-levels was named after him. A 29 floor L-shaped building called Caine House, part of the Hong Kong Police Headquarters, was named after him and completed 1987.