The Wellington and Drayton Railway was a standard gauge line in Central England which carried through freight and local passenger traffic until closure in the 1960s. It was part of the Great Western Railway's double track Wellington-Crewe line, linking the Midlands to the north and northwest.
The Wellington and Drayton Railway was incorporated on 7 August 1862, and in November of that year deposited plans for a line connecting Wellington to Market Drayton, together with extensions northwards towards Manchester, to join the LNWR near Minshull Vernon, the Cheshire Midland Railway near Knutsford, the Manchester South Junction and Altrincham Railway and the Bolton Railway at Salford, to provide the Great Western Railway with access to Manchester. Additionally there were plans for a branch from Market Drayton to Newcastle-under-Lyme, but these were abandoned due to opposition from the LNWR and North Staffordshire Railway.
Circumstances changed rapidly, and alliance with the Nantwich and Market Drayton Railway together with running powers from Nantwich to Crewe and onwards to Manchester through amalgamation of the Great Western Railway with the West Midland Railway meant that the northern extensions were no longer needed by the GWR for access to Manchester.