The Walkerton E. coli outbreak (also known as the Walkerton tragedy) occurred in May 2000 when Escherichia coli O157:H7 (a dangerous strain of pathogenic Escherichia coli bacteria) contaminated the water supply of the small community of Walkerton, Ontario, Canada. As a result, seven people died and thousands were sickened.
At the time of the event in May 2000, Stan Koebel was utilities manager for Walkerton, and his brother Frank Koebel was water foreman. Neither had any formal training in this position, retaining their jobs through three decades of on-the-job experience. The water supply, drawn from groundwater, became contaminated with the highly dangerous O157:H7 strain of E. coli bacteria. This contamination was due to farm runoff into an adjacent water well that had been known for years to be vulnerable to groundwater contamination.
Starting May 13, 2000, many people of the community of about 5,000 people began to experience bloody diarrhea, gastrointestinal infections and other symptoms of E. coli infection. For days the Walkerton Public Utilities Commission insisted the water supply was "OK" despite being in possession of laboratory tests that had found evidence of contamination. On 21 May, an escalation in the number of patients with similar symptoms finally spurred the region's Medical Officer of Health, Murray McQuigge, to issue a boil-water advisory, warning residents not to drink the tapwater.
The five people who died directly from drinking the E. coli-contaminated water might have been saved if the Walkerton Public Utilities Commission had admitted to contaminated water sooner, and about 2,500 became ill. An experimental drug in Phase III clinical trials, Synsorb Pk, was used to treat 19 children on compassionate grounds under Health Canada's Special Access Program.