WDR5

WDR5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CNX, 2CO0, 2G99, 2G9A, 2GNQ, 2H13, 2H14, 2H68, 2H6K, 2H6N, 2H6Q, 2H9L, 2H9M, 2H9N, 2H9P, 2O9K, 3EG6, 3EMH, 3MXX, 3N0D, 3N0E, 3P4F, 3PSL, 3SMR, 3UR4, 3UVK, 3UVL, 3UVM, 3UVN, 3UVO, 4A7J, 4CY1, 4CY2, 4ERQ, 4ERY, 4ERZ, 4ES0, 4ESG, 4EWR, 4GM3, 4GM8, 4GM9, 4GMB, 4IA9, 4O45, 4QL1, 4Y7R, 5EAL, 5EAP, 5EAR, 4QQE, 5EAM
Identifiers
Aliases	WDR5, BIG-3, CFAP89, SWD3, WD repeat-containing protein 5, WD repeat domain 5
External IDs	MGI: 2155884 HomoloGene: 59931 GeneCards: WDR5
Gene ontology Molecular function • histone methyltransferase activity (H3-K4 specific) • histone acetyltransferase activity (H4-K8 specific) • histone acetyltransferase activity (H4-K5 specific) • methylated histone binding • protein binding • histone acetyltransferase activity (H4-K16 specific) • histone-lysine N-methyltransferase activity Cellular component • Ada2/Gcn5/Ada3 transcription activator complex • Set1C/COMPASS complex • intracellular • nucleoplasm • MLL1 complex • MLL3/4 complex • histone acetyltransferase complex • nucleus • histone methyltransferase complex • ciliary basal body Biological process • skeletal system development • regulation of transcription, DNA-templated • transcription, DNA-templated • histone H4-K5 acetylation • histone H3-K4 methylation • histone H3 acetylation • histone H4-K16 acetylation • neuron projection development • histone H4-K8 acetylation • positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter • covalent chromatin modification • cilium morphogenesis • post-translational protein modification • regulation of megakaryocyte differentiation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11091	140858
Ensembl	ENSG00000196363	ENSMUSG00000026917
UniProt	P61964	P61965
RefSeq (mRNA)	NM_017588 NM_052821	NM_080848
RefSeq (protein)	NP_060058 NP_438172	NP_543124
Location (UCSC)	Chr 9: 134.14 – 134.16 Mb	Chr 2: 27.52 – 27.54 Mb
PubMed search

2CNX, 2CO0, 2G99, 2G9A, 2GNQ, 2H13, 2H14, 2H68, 2H6K, 2H6N, 2H6Q, 2H9L, 2H9M, 2H9N, 2H9P, 2O9K, 3EG6, 3EMH, 3MXX, 3N0D, 3N0E, 3P4F, 3PSL, 3SMR, 3UR4, 3UVK, 3UVL, 3UVM, 3UVN, 3UVO, 4A7J, 4CY1, 4CY2, 4ERQ, 4ERY, 4ERZ, 4ES0, 4ESG, 4EWR, 4GM3, 4GM8, 4GM9, 4GMB, 4IA9, 4O45, 4QL1, 4Y7R, 5EAL, 5EAP, 5EAR, 4QQE, 5EAM

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