WASF1

WASF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3P8C, 4N78
Identifiers
Aliases	WASF1, SCAR1, WAVE, WAVE1, WAS protein family member 1
External IDs	MGI: 1890563 HomoloGene: 2920 GeneCards: WASF1
Gene ontology Molecular function • protein complex binding • actin binding • Rac GTPase binding • protein binding Cellular component • cytoplasm • mitochondrial outer membrane • cell junction • synapse • cytoskeleton • mitochondrion • SCAR complex • lamellipodium • focal adhesion • actin cytoskeleton Biological process • movement of cell or subcellular component • actin filament polymerization • Rac protein signal transduction • positive regulation of Arp2/3 complex-mediated actin nucleation • lamellipodium morphogenesis • actin cytoskeleton organization • protein complex assembly • neuron projection development • positive regulation of neurotrophin TRK receptor signaling pathway • dendrite extension • receptor-mediated endocytosis • cellular response to brain-derived neurotrophic factor stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8936	83767
Ensembl	ENSG00000112290	ENSMUSG00000019831
UniProt	Q92558	Q8R5H6
RefSeq (mRNA)	NM_001024934 NM_001024935 NM_001024936 NM_003931	NM_031877
RefSeq (protein)	NP_001020105 NP_001020106 NP_001020107 NP_003922	NP_114083.1 NP_114083
Location (UCSC)	Chr 6: 110.1 – 110.18 Mb	Chr 10: 40.88 – 40.94 Mb
PubMed search

3P8C, 4N78

8936

83767

ENSG00000112290

ENSMUSG00000019831

Q92558

Q8R5H6

NM_001024934
NM_001024935
NM_001024936
NM_003931

NM_031877

NP_001020105
NP_001020106
NP_001020107
NP_003922

NP_114083.1
NP_114083

Wiskott-Aldrich syndrome protein family member 1, also known as WASP-family verprolin homologous protein 1 (WAVE1), is a protein that in humans is encoded by the WASF1 gene.

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Wikipedia