Don't miss the special BONUS offer during our Beta-test period. The next 100 new Registered Users (from a unique IP address), to post at least five (5) piglix, will receive 1,000 extra sign-up points (eventually exchangeable for crypto-currency)!

* * * * *    Free Launch Promotions    * * * * *

  • Free Ads! if you are a small business with annual revenues of less than $1M - will place your ads free of charge for up to one year! ... read more

  • $2,000 in free prizes! is giving away ten (10) Meccano Erector sets, retail at $200 each, that build a motorized Ferris Wheel (or one of 22 other models) ... see details

Vitamin B6

Vitamin B6
Drug class
The chemical structure of pyridoxal phosphate, a form of vitamin B6.
Class identifiers
Use Vitamin B6 deficiency
ATC code A11HA02
Biological target enzyme cofactor
Clinical data International Drug Names
External links
MeSH D025101

Vitamin B6 refers to a group of chemically very similar compounds which can be interconverted in biological systems. Vitamin B6 is part of the vitamin B group, and its active form, pyridoxal 5′-phosphate (PLP) serves as a coenzyme in many enzyme reactions in amino acid, glucose, and lipid metabolism.

Several forms (vitamers) of vitamin B6 are known:

All forms except pyridoxic acid and pyritinol can be interconverted. Absorbed pyridoxamine is converted to PMP by pyridoxal kinase, which is further converted to PLP by pyridoxamine-phosphate transaminase or pyridoxine 5′-phosphate oxidase which also catalyzes the conversion of PNP to PLP. Pyridoxine 5′-phosphate oxidase is dependent on flavin mononucleotide (FMN) as a cofactor which is produced from riboflavin (vitamin B2) i.e. in this biochemical pathway, dietary vitamin B6 cannot be used without vitamin B2.

PLP, the metabolically active form of vitamin B6, is involved in many aspects of macronutrient metabolism, neurotransmitter synthesis, histamine synthesis, hemoglobin synthesis and function, and gene expression. PLP generally serves as a coenzyme (cofactor) for many reactions including decarboxylation, transamination, racemization, elimination, replacement, and beta-group interconversion. The liver is the site for vitamin B6 metabolism.



Don't forget! that as one of our early users, you are eligible to receive the 1,000 point bonus as soon as you have created five (5) acceptable piglix.