Victor Frederick of Anhalt-Bernburg (20 September 1700–18 May 1765), was a German prince of the House of Ascania. He was Reigning prince of the principality of Anhalt-Bernburg from 1721 to 1765.

Victor Frederick was born on 20 September 1700 in Bernburg as the second (but eldest and only surviving) son of Karl Frederick, Prince of Anhalt-Bernburg, by his first wife Sophie Albertine, daughter of George Frederick, Count of Solms-Sonnenwalde.

After the death of his father in 1721, Victor Frederick succeeded him in Anhalt-Bernburg. As a Rittmeister and Capitan of the Prussian army, he was made a knight of the Order of the Black Eagle in 1722.

Victor Frederick showed a special interest for mining and metallurgy and often visited the mines in the Harz.

He died on 18 May 1765 in Bernburg.

In Dessau on 25 November 1724 Victor Frederick married Louise (b. Dessau, 21 August 1709 - d. Bernburg, 29 July 1732), daughter of Leopold I, Prince of Anhalt-Dessau. They had one daughter:

In Potsdam on 22 May 1733 Victor Frederick married for a second time to Sophie Albertine Fredericka (b. Berlin, 21 April 1712 - d. Bernburg, 7 September 1750), daughter of Margrave Albert Frederick of Brandenburg-Schwedt. They had five children:

In Bernburg on 13 November 1750 Victor Frederick married morganatically for a third time to Konstanze Fredericka Schmidt, a commoner. She was ennobled and obtain the title of Baroness of Bähr (German: Frau von Bähr) in 1752, shortly before the birth of their only daughter:

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