Vascular cell adhesion molecule-1

VCAM1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1IJ9, 1VCA, 1VSC
Identifiers
Aliases	VCAM1, CD106, INCAM-100, vascular cell adhesion molecule 1
External IDs	OMIM: 192225 MGI: 98926 HomoloGene: 838 GeneCards: VCAM1
Gene location (Human) Chr. Chromosome 1 (human) Band 1p21.2 Start 100,719,742 bp End 100,739,045 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3 G1|3 50.17 cM Start 116,109,949 bp End 116,129,688 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • primary amine oxidase activity • integrin binding • cell adhesion molecule binding Cellular component • integral component of membrane • Golgi apparatus • alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex • membrane • filopodium • plasma membrane • apical part of cell • microvillus • cell surface • early endosome • endoplasmic reticulum • podosome • sarcolemma • extracellular exosome • external side of plasma membrane • extracellular space Biological process • leukocyte cell-cell adhesion • response to ionizing radiation • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • response to hypoxia • response to nutrient • interferon-gamma-mediated signaling pathway • cellular response to tumor necrosis factor • response to nicotine • aging • response to zinc ion • extracellular matrix organization • amine metabolic process • response to lipopolysaccharide • cell adhesion • acute inflammatory response • positive regulation of T cell proliferation • membrane to membrane docking • regulation of immune response • leukocyte tethering or rolling • cell chemotaxis • B cell differentiation • cellular response to vascular endothelial growth factor stimulus • cell-matrix adhesion • viral process • response to ethanol • calcium-mediated signaling using intracellular calcium source • chronic inflammatory response • oxidation-reduction process • cell-cell adhesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	7412	22329
Ensembl	ENSG00000162692	ENSMUSG00000027962
UniProt	P19320	P29533
RefSeq (mRNA)	NM_080682 NM_001078 NM_001199834	NM_011693
RefSeq (protein)	NP_001069 NP_001186763 NP_542413	NP_035823
Location (UCSC)	Chr 1: 100.72 – 100.74 Mb	Chr 3: 116.11 – 116.13 Mb
PubMed search

1IJ9, 1VCA, 1VSC

7412

22329

ENSG00000162692

ENSMUSG00000027962

P19320

P29533

NM_080682
NM_001078
NM_001199834

NM_011693

NP_001069
NP_001186763
NP_542413

NP_035823

Vascular cell adhesion protein 1 also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106) is a protein that in humans is encoded by the VCAM1 gene. VCAM-1 functions as a cell adhesion molecule.

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