USP8

USP8

Protein USP8 PDB 1whb.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WHB, 2A9U, 2GFO, 2GWF, 3N3K

Identifiers

USP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8

External IDs

MGI: 1934029 HomoloGene: 3782 GeneCards: USP8

Gene ontology
Molecular function	• cysteine-type peptidase activity • SH3 domain binding • thiol-dependent ubiquitinyl hydrolase activity • peptidase activity • protein binding • thiol-dependent ubiquitin-specific protease activity • cysteine-type endopeptidase activity • hydrolase activity • cadherin binding
Cellular component	• cytoplasm • cytosol • endosome • membrane • plasma membrane • extrinsic component of endosome membrane • midbody • early endosome • endosome membrane • extrinsic component of plasma membrane • nucleus • postsynaptic density • dendritic spine
Biological process	• protein K48-linked deubiquitination • ubiquitin-dependent protein catabolic process • mitotic cytokinesis • endosome organization • proteolysis • protein K63-linked deubiquitination • cell cycle • cell proliferation • protein deubiquitination
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


9101


84092


ENSG00000138592


ENSMUSG00000027363


P40818


Q80U87

RefSeq (mRNA)


NM_001128610 NM_001128611 NM_001283049 NM_005154


NM_001252580 NM_019729

RefSeq (protein)


NP_001122082 NP_001269978 NP_005145


NP_062703.2 NP_001239509 NP_062703

Location (UCSC)

Chr 15: 50.42 – 50.51 Mb

Chr 2: 126.71 – 126.76 Mb

PubMed search

1WHB, 2A9U, 2GFO, 2GWF, 3N3K

ENSG00000138592

ENSMUSG00000027363

NM_001128610
NM_001128611
NM_001283049
NM_005154

NM_001252580
NM_019729

NP_001122082
NP_001269978
NP_005145

NP_062703.2
NP_001239509
NP_062703

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Wikipedia

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