UMP synthase

UMPS
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4HKP, 2EAW, 2JGY, 2P1F, 2QCC, 2QCD, 2QCE, 2QCF, 2QCG, 2QCH, 2QCL, 2QCM, 2QCN, 2V30, 2WNS, 3BGG, 3BGJ, 3BK0, 3BVJ, 3DBP, 3EWU, 3EWW, 3EWX, 3EWY, 3EWZ, 3EX1, 3EX2, 3EX3, 3EX4, 3EX6, 3G3D, 3G3M, 3L0K, 3L0N, 3MI2, 3MO7, 3MW7, 4HIB
Identifiers
Aliases	UMPS, OPRT, uridine monophosphate synthetase
External IDs	OMIM: 613891 MGI: 1298388 HomoloGene: 319 GeneCards: UMPS
Gene ontology Molecular function • lyase activity • carboxy-lyase activity • transferase activity • catalytic activity • transferase activity, transferring glycosyl groups • orotidine-5'-phosphate decarboxylase activity • orotate phosphoribosyltransferase activity Cellular component • cytoplasm • cytosol • nucleus Biological process • female pregnancy • cellular response to drug • pyrimidine nucleotide biosynthetic process • UMP biosynthetic process • metabolic process • nucleoside metabolic process • pyrimidine nucleoside biosynthetic process • 'de novo' UMP biosynthetic process • 'de novo' pyrimidine nucleobase biosynthetic process • lactation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7372	22247
Ensembl	ENSG00000114491	ENSMUSG00000022814
UniProt	P11172	P13439
RefSeq (mRNA)	NM_000373	NM_009471 NM_001348087
RefSeq (protein)	NP_000364	NP_033497.1 NP_033497 NP_001335016
Location (UCSC)	Chr 3: 124.73 – 124.75 Mb	Chr 16: 33.95 – 33.97 Mb
PubMed search

4HKP, 2EAW, 2JGY, 2P1F, 2QCC, 2QCD, 2QCE, 2QCF, 2QCG, 2QCH, 2QCL, 2QCM, 2QCN, 2V30, 2WNS, 3BGG, 3BGJ, 3BK0, 3BVJ, 3DBP, 3EWU, 3EWW, 3EWX, 3EWY, 3EWZ, 3EX1, 3EX2, 3EX3, 3EX4, 3EX6, 3G3D, 3G3M, 3L0K, 3L0N, 3MI2, 3MO7, 3MW7, 4HIB

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