UFC Fight Night: Namajunas vs. VanZant (also known as UFC Fight Night 80) was a mixed martial arts event held on December 10, 2015 at The Chelsea at The Cosmopolitan in Las Vegas, Nevada.

The event was expected to be headlined by a women's strawweight bout between Paige VanZant and Joanne Calderwood. However on October 28, Calderwood was forced to pull out of the event and was replaced by Rose Namajunas.

The event was the first that the promotion has hosted at the venue and the first of three events in as many days in the Las Vegas Valley. It also marked the first North American card to air live exclusively on their subscription-based digital network, UFC Fight Pass.

A welterweight bout between Sheldon Westcott and Edgar Garcia, originally scheduled for this event was moved to UFC 195.

Lyman Good was expected to face Omari Akhmedov at the event. However, Good was pulled from the bout in late October and was replaced by Sérgio Moraes.

Michael Graves was expected to face Danny Roberts at the event. However, Graves pulled out of the bout on November 30 citing an injury and was replaced by Nathan Coy.

The following fighters were awarded $50,000 bonuses:

The following is the reported payout to the fighters as reported to the Nevada State Athletic Commission. It does not include sponsor money and also does not include the UFC's traditional "fight night" bonuses.

^ Both fighters earned show money (Casey awarded win Bonus); bout declared No Contest.

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