UBE2N

UBE2N
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1J7D, 2C2V, 3HCT, 3HCU, 3VON, 3W31, 4DHI, 4DHJ, 4DHZ, 4IP3, 4NR3, 4NRG, 4NRI, 4ONL, 4ONM, 4ONN, 4ORH, 4TKP, 5AIT, 5AIU, 4WHV
Identifiers
Aliases	UBE2N, HEL-S-71, UBC13, UBCHBEN; UBC13, UbcH-ben, UbcH13, ubiquitin conjugating enzyme E2 N
External IDs	MGI: 1934835 HomoloGene: 128406 GeneCards: UBE2N
Gene ontology Molecular function • transferase activity • nucleotide binding • ubiquitin protein ligase activity • ubiquitin binding • protein binding • ATP binding • ubiquitin protein ligase binding • RNA binding • ubiquitin-protein transferase activity • ubiquitin conjugating enzyme activity Cellular component • cytoplasm • cytosol • UBC13-UEV1A complex • ubiquitin ligase complex • protein complex • nucleoplasm • extracellular exosome • UBC13-MMS2 complex • nucleus • fibrillar center Biological process • postreplication repair • protein K63-linked ubiquitination • regulation of DNA repair • DNA double-strand break processing • positive regulation of DNA repair • stimulatory C-type lectin receptor signaling pathway • proteolysis • cellular response to DNA damage stimulus • Fc-epsilon receptor signaling pathway • global genome nucleotide-excision repair • positive regulation of histone modification • cellular protein modification process • positive regulation of ubiquitin-protein transferase activity • protein ubiquitination • regulation of histone ubiquitination • positive regulation of I-kappaB kinase/NF-kappaB signaling • T cell receptor signaling pathway • double-strand break repair via nonhomologous end joining • nucleotide-binding oligomerization domain containing signaling pathway • histone ubiquitination • DNA repair • double-strand break repair via homologous recombination • activation of MAPK activity • JNK cascade • positive regulation of NF-kappaB transcription factor activity • ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	7334	93765
Ensembl	ENSG00000177889	ENSMUSG00000074781
UniProt	P61088	P61089
RefSeq (mRNA)	NM_003348	NM_080560
RefSeq (protein)	NP_003339	NP_542127
Location (UCSC)	Chr 12: 93.41 – 93.44 Mb	Chr 10: 95.52 – 95.55 Mb
PubMed search

1J7D, 2C2V, 3HCT, 3HCU, 3VON, 3W31, 4DHI, 4DHJ, 4DHZ, 4IP3, 4NR3, 4NRG, 4NRI, 4ONL, 4ONM, 4ONN, 4ORH, 4TKP, 5AIT, 5AIU, 4WHV

7334

93765

ENSG00000177889

ENSMUSG00000074781

...
Wikipedia