U1-RNP

SNRNP70
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2L5I, 2L5J, 3CW1, 3PGW, 4PJO, 4PKD
Identifiers
Aliases	SNRNP70, RNPU1Z, RPU1, SNRP70, Snp1, U1-70K, U170K, U1AP, U1RNP, SnRNP70, small nuclear ribonucleoprotein U1 subunit 70
External IDs	MGI: 98341 HomoloGene: 20672 GeneCards: SNRNP70
Gene ontology Molecular function • nucleotide binding • protein binding • nucleic acid binding • mRNA binding • U1 snRNP binding • U1 snRNA binding • RNA binding Cellular component • nuclear speck • intracellular ribonucleoprotein complex • nucleoplasm • precatalytic spliceosome • spliceosomal complex • commitment complex • U2-type prespliceosome • nucleus • U1 snRNP • cytoplasm Biological process • mRNA splicing, via spliceosome • positive regulation of mRNA splicing, via spliceosome • mRNA processing • negative regulation of chaperone-mediated autophagy • regulation of RNA splicing • RNA splicing • regulation of ATPase activity • negative regulation of protein refolding • cellular response to tumor necrosis factor • cellular response to retinoic acid • cellular response to transforming growth factor beta stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6625	20637
Ensembl	ENSG00000104852	ENSMUSG00000063511
UniProt	P08621	Q62376
RefSeq (mRNA)	NM_001009820 NM_001301069 NM_003089	NM_009224
RefSeq (protein)	NP_001287998 NP_003080	NP_033250.3 NP_033250
Location (UCSC)	Chr 19: 49.09 – 49.11 Mb	Chr 7: 45.38 – 45.4 Mb
PubMed search

2L5I, 2L5J, 3CW1, 3PGW, 4PJO, 4PKD

6625

20637

ENSG00000104852

ENSMUSG00000063511

P08621

Q62376

NM_001009820
NM_001301069
NM_003089

NM_009224

NP_001287998
NP_003080

NP_033250.3
NP_033250

snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the SNRNP70 gene. snRNP70 is a small nuclear ribonucleoprotein that associates with U1 spliceosomal RNA, forming part of the spliceosome.

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Wikipedia