Transferrin receptor 1

TFRC

Protein TFRC PDB 1cx8.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1CX8, 1DE4, 1SUV, 2NSU, 3KAS, 3S9L, 3S9M, 3S9N

Identifiers

TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90, IMD46, transferrin receptor

External IDs

MGI: 98822 HomoloGene: 2429 GeneCards: TFRC

Gene ontology
Molecular function	• protein homodimerization activity • virus receptor activity • glycoprotein binding • transferrin receptor activity • protein binding • identical protein binding • double-stranded RNA binding • transferrin transmembrane transporter activity • RNA binding
Cellular component	• extracellular vesicle • integral component of membrane • recycling endosome • HFE-transferrin receptor complex • endosome • blood microparticle • membrane • melanosome • plasma membrane • integral component of plasma membrane • extracellular region • cell surface • basolateral plasma membrane • perinuclear region of cytoplasm • clathrin-coated pit • extracellular exosome • external side of plasma membrane • extracellular space • clathrin-coated vesicle membrane • cytoplasmic vesicle • endosome membrane
Biological process	• endocytosis • osteoclast differentiation • positive regulation of bone resorption • receptor-mediated endocytosis • iron ion import • cellular response to drug • regulation of cell proliferation • regulation of cell growth • viral entry into host cell • viral process • cellular iron ion homeostasis • positive regulation of isotype switching • receptor internalization • transferrin transport • positive regulation of B cell proliferation • positive regulation of T cell proliferation • membrane organization
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE TFRC 208691 at fs.png

PBB GE TFRC 207332 s at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


7037


22042


ENSG00000072274


ENSMUSG00000022797


P02786


Q62351

RefSeq (mRNA)


NM_001313965 NM_001313966 NM_001128148 NM_003234


NM_011638

RefSeq (protein)


NP_001121620 NP_001300894 NP_001300895 NP_003225


NP_035768.1 NP_035768

Location (UCSC)

Chr 3: 196.03 – 196.08 Mb

Chr 16: 32.61 – 32.63 Mb

PubMed search

1CX8, 1DE4, 1SUV, 2NSU, 3KAS, 3S9L, 3S9M, 3S9N

ENSG00000072274

ENSMUSG00000022797

NM_001313965
NM_001313966
NM_001128148
NM_003234

NP_001121620
NP_001300894
NP_001300895
NP_003225

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Wikipedia

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